Week 6 Trends: Upsets Shake Spreads in NFL 2025

October 12, 2025 | 6 min read

Week 6 of the 2025 NFL season brought upsets, per Spreadspoke’s dataset ($24.99/year, weekly updates). With data from nfl_2025.csv, we examine this volatility. Data is for research only—see our footer for responsible gambling resources.

Week 6 Overview

Week 6 had 13 games, with a 46.2% upset rate shaking up spreads, like Miami vs. Indianapolis.

Data Analysis: Upset Games

Key games from Week 6:

GameFavoriteSpreadResultATS Outcome
MIA @ INDMIA-728-25IND covers
TB @ ATLATL-4.524-21TB covers

Upsets occurred in 6 of 13 games (46.2%).

Chart: Upset Frequency

The chart shows the upset rate in Week 6.

Historical Context

Week 6 upsets average 40% historically (1966–2024), making 2025 slightly above average.

Key Takeaways

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